5361-15-9
5361-15-9 structure
- Name: GMQ hydrochloride
- Chemical Name: 1-(4-Methyl-2-quinazolinyl)guanidine hydrochloride (1:1)
- CAS Number: 5361-15-9
- Molecular Formula: C10H12ClN5
- Molecular Weight: 237.68900
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
- Create Date: 2017-01-13 05:23:11
- Modify Date: 2024-01-02 18:58:36
-
GMQ is a ASIC (acid-sensing ion) channel activator with an EC50 value of 1.83 mM for ASIC3 at pH 7.4. GMQ opens only ASIC3 but no other ASICs at pH 7.4. GMQ can be used for neurological disease research[1].
| Name | 1-(4-Methyl-2-quinazolinyl)guanidine hydrochloride (1:1) |
|---|---|
| Synonyms |
D-Amphetamine sulfate
2-GUANIDINO-4-METHYLQUINAZOLINE HYDROCHLORIDE |
| Description | GMQ is a ASIC (acid-sensing ion) channel activator with an EC50 value of 1.83 mM for ASIC3 at pH 7.4. GMQ opens only ASIC3 but no other ASICs at pH 7.4. GMQ can be used for neurological disease research[1]. |
|---|---|
| Related Catalog | |
| In Vitro | GMQ (1 mM) 在 pH 7.4 的条件下，产生持续向内电流在 CHO 细胞中[1]。 GMQ 在高浓度时阻断 ASIC 孔隙，对 ASIC1a，ASIC1b 和 ASIC3 的 IC50 值分别为 3.24，1.52 和 6.74 mM[1]。 |
| References |
| Molecular Formula | C10H12ClN5 |
|---|---|
| Molecular Weight | 237.68900 |
| Exact Mass | 237.07800 |
| PSA | 87.68000 |
| LogP | 2.91860 |
| Storage condition | -20°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2933990090 |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |