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872992-20-6

872992-20-6 structure
872992-20-6 structure
  • Name: (R)-Linezolid
  • Chemical Name: N-[[(5R)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
  • CAS Number: 872992-20-6
  • Molecular Formula: C16H20FN3O4
  • Molecular Weight: 337.346
  • Catalog: Research Areas Infection
  • Create Date: 2016-06-28 19:47:46
  • Modify Date: 2024-01-28 17:22:19
  • (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis[1][2].

Name N-[[(5R)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
Synonyms Acetamide, N-[[(5R)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-
UNII-ISQ9I6J12J
N-({(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
Zivoxid
N-({(5R)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
Linezolid Impurity 1
Description (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis[1][2].
Related Catalog
References

[1]. Bednarek E, et al. NMR and molecular modeling study, as complementary techniques to capillary electrophoresis method to elucidate the separation mechanism of linezolid enantiomers. J Chromatogr A. 2008 Jun 6;1193(1-2):164-71.

[2]. Clemett D, et al. Linezolid. Drugs. 2000 Apr;59(4):815-27; discussion 828.

Density 1.3±0.1 g/cm3
Boiling Point 585.5±50.0 °C at 760 mmHg
Molecular Formula C16H20FN3O4
Molecular Weight 337.346
Flash Point 307.9±30.1 °C
Exact Mass 337.143799
PSA 74.60000
LogP 0.30
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.554
RIDADR NONH for all modes of transport