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868594-52-9

868594-52-9 structure
868594-52-9 structure
  • Name: Fmoc-NH-PEG8-CH2COOH
  • Chemical Name: 26-(fluoren-9-ylmethyloxycarbonylamino)-3,6,9,12,15,18,21,24-octaoxahexaeicosanoic acid
  • CAS Number: 868594-52-9
  • Molecular Formula: C33H47NO12
  • Molecular Weight: 649.72600
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2019-01-10 16:39:01
  • Modify Date: 2024-01-06 17:41:23
  • Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name 26-(fluoren-9-ylmethyloxycarbonylamino)-3,6,9,12,15,18,21,24-octaoxahexaeicosanoic acid
Synonyms Fmoc-NH-PEG8-CH2COOH
FMOC-NH-DPEG8-COOH
5,8,11,14,17,20,23,26-Octaoxa-2-azaoctacosanedioic acid 1-(9H-fluoren-9-ylmethyl) ester
Fmoc-NH-8(ethylene glycol)-acetic acid
Fmoc-NH-8(ethylene glycol)-actic acid
Description Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Michael A, et al. Synthesis of Bifunctional Integrin‐Binding Peptides Containing PEG Spacers of Defined Length for Non‐Viral Gene Delivery. Volume2008, Issue17.

Molecular Formula C33H47NO12
Molecular Weight 649.72600
Exact Mass 649.31000
PSA 149.47000
LogP 3.13340
Hazard Codes Xi