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623-58-5

623-58-5 structure
623-58-5 structure
  • Name: Acetoacetic acid sodium salt
  • Chemical Name: sodium,3-oxobutanoate
  • CAS Number: 623-58-5
  • Molecular Formula: C4H5NaO3
  • Molecular Weight: 124.07
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2016-10-30 16:26:52
  • Modify Date: 2024-01-03 23:13:56
  • Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes. Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes[1].

Name sodium,3-oxobutanoate
Synonyms Butanoic acid,3-oxo-,sodium salt
sodium acetoacetic acid ester
sodium acetoxyacetate
sodium 3-oxobutanoate
sodium acetylacetonate
acetoacetic acid,monosodium salt
Sodium Acetoacetate
Acetylacetic Acid Sodium salt
Acetoacetic acid sodium salt
Description Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes. Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes[1].
Related Catalog
In Vitro Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes[1]. Acetoacetic acid (0.6, 2.4, 4.8 mM) increases malondialdehyde (MDA) content in high-dose group (GH) group, decreases mRNA expression of Mn SOD, Cu/Zn SOD, and glutathione peroxidase (GSH-Px) in all groups, lowers catalase (CAT) mRNA expression in medial-dose group (GM), and GH groups. In addition, Acetoacetic acid down-regulates the mRNA expression of apolipoprotein B100 (ApoB100), apolipoprotein E (ApoE), and low density lipoprotein receptor (LDLR). Thus, VLDL assembly is decreased andtriglyceride (TG) accumulation is increased in these bovine hepatocytes[1].
References

[1]. Shi X, et al. Acetoacetic acid induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes. J Dairy Res. 2016 Nov;83(4):442-446.

Boiling Point 237.7ºC at 760 mmHg
Molecular Formula C4H5NaO3
Molecular Weight 124.07
Flash Point 111.8ºC
Exact Mass 124.01400
PSA 57.20000
HS Code 2918300090

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Detail
Literature: Nippon Soda Co., Ltd. Patent: US5484949 A1, 1996 ;

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623-58-5 structure

623-58-5

Literature: BASF Aktiengesellschaft Patent: US5428174 A1, 1995 ;

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623-58-5 structure

623-58-5

Literature: Tommasi, Immacolata; Sorrentino, Fabiana Tetrahedron Letters, 2009 , vol. 50, # 1 p. 104 - 107

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623-58-5 structure

623-58-5

Literature: Goemez-Bombarelli, Rafael; Gonzalez-Perez, Marina; Perez-Prior, Maria Teresa; Manso, Jose A.; Calle, Emilio; Casado, Julio Journal of Physical Organic Chemistry, 2009 , vol. 22, # 5 p. 438 - 442

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623-58-5 structure

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Literature: Franklin, M. C.; Short, W. F. Journal of the Chemical Society, 1928 , p. 591 - 595
HS Code 2918300090
Summary 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%