Name | Rapamycin-d3 |
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Synonyms |
[2H3]-Sirolimus
Rapamycin,7-O-demethyl-7-O-(methyl-d3) |
Description | Rapamycin-d3 (Sirolimus-d3) is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC50of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1[1]. Rapamycin is an autophagy activator, an immunosuppressant[2]. |
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Related Catalog | |
References |
Molecular Formula | C51H76D3NO13 |
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Molecular Weight | 917.19000 |
Exact Mass | 916.57400 |
PSA | 195.43000 |
LogP | 6.11850 |
Hazard Codes | Xi |
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