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5704-60-9

5704-60-9 structure
5704-60-9 structure
  • Name: Nifenalol
  • Chemical Name: Nifenalol hydrochloride
  • CAS Number: 5704-60-9
  • Molecular Formula: C11H17ClN2O3
  • Molecular Weight: 260.72
  • Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
  • Create Date: 2017-04-06 08:13:57
  • Modify Date: 2024-01-11 12:26:42
  • Nifenalol hydrochloride is a β-adrenergic receptor antagonist. Nifenalol hydrochloride induces the Early Afterdepolarization (EAD) effect. EAD is a phenomenon in cardiac electrophysiology that usually occurs during an action potential in ventricular muscle cells and can lead to arrhythmia. The EAD effect of Nifenalol hydrochloride can be blocked by Tetrodotoxin. Nifenalol hydrochloride is used in the study of conditions such as irregular heartbeat or high blood pressure[1].

Name Nifenalol hydrochloride
Synonyms INPEA hydrochloride
N-isopropyl-p-nitrophenylethanolamine hydrochloride
Nifenalol
Description Nifenalol hydrochloride is a β-adrenergic receptor antagonist. Nifenalol hydrochloride induces the Early Afterdepolarization (EAD) effect. EAD is a phenomenon in cardiac electrophysiology that usually occurs during an action potential in ventricular muscle cells and can lead to arrhythmia. The EAD effect of Nifenalol hydrochloride can be blocked by Tetrodotoxin. Nifenalol hydrochloride is used in the study of conditions such as irregular heartbeat or high blood pressure[1].
Related Catalog
Target

β-adrenoceptor

References

[1]. Lemmens-Gruber R, et al. Arrhythmogenic effect of beta-adrenoceptor-blocking drugs in Purkinje fibres of guinea-pig hearts. Arch Int Pharmacodyn Ther. 1996 Jan-Feb;331(1):46-58.  

Molecular Formula C11H17ClN2O3
Molecular Weight 260.72
Exact Mass 260.09300
PSA 78.08000
LogP 3.34230
HS Code 2922199090
Precursor  0

DownStream  1

HS Code 2922199090
Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%