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18598-63-5

18598-63-5 structure
18598-63-5 structure

Name methyl (2R)-2-amino-3-sulfanylpropanoate,hydrochloride
Synonyms Actiol
H-Cys-OMe·HCl
Mecystein HCl
cysteine methyl ester hydrochloride
methyl L-cysteinate hydrochloride
Acdrile
MFCD00038985
Methyl L-cysteinate hydrochloride (1:1)
EINECS 242-435-0
L-Cysteine, methyl ester, hydrochloride (1:1)
hydrochloride*H-Cys-OMe
Methyl cysteine HCl
H-Cys-OMe.HCl
L-Cysteine Methyl Ester Hydrochloride
L-Cysteinemethylesterhydrochloride
Description Mecysteine hydrochloride is an antitussive, and an expectorant agent, used to relieve breathing difficulties caused by mucus.
Related Catalog
Boiling Point 197.2ºC at 760 mmHg
Melting Point 142 °C (dec.)(lit.)
Molecular Formula C4H10ClNO2S
Molecular Weight 171.646
Flash Point 73.1ºC
Exact Mass 171.012070
PSA 91.12000
LogP 0.91880
Vapour Pressure 0.384mmHg at 25°C
Index of Refraction -2.5 ° (C=20, MeOH)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HA2460000
CHEMICAL NAME :
Cysteine, methyl ester, hydrochloride, L-
CAS REGISTRY NUMBER :
18598-63-5
LAST UPDATED :
199210
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C4-H9-N-O2-S.Cl-H
MOLECULAR WEIGHT :
171.66
WISWESSER LINE NOTATION :
SH1YZVO1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 24,2331,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1340 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,829,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
60 gm/kg/30D-C
TOXIC EFFECTS :
Liver - other changes Kidney, Ureter, Bladder - other changes Blood - normocytic anemia
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 14,1407,1980
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS HA2460000
HS Code 2930909090
HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%