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90-80-2

90-80-2 structure
90-80-2 structure

Name D-glucono-1,5-lactone
Synonyms D-Gluconolactone
EINECS 202-016-5
δ-Gluconolactone
(3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-one
D-Gluconic acid-1,5-lactone
D-Glucono-1,5-lactone
D-Glucono-d-lactone
gluconolactone
D-Gluconic acid 1,5-lactone
d-gluconic acid d-lactone
Delta-Gluconolactone
Gluconic acid lactone
δ-Gluconic acid d-lactone
δ-Gluconic acid δ-lactone
MFCD00006647
Glucono δ-lactone
D-Gluconic acid lactone
D-Gluconic acid, δ-lactone
D-(+)-Glucono-1,5-lactone
Description D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro D-(+)-Glucono-1,5-lactone is a lactone (cyclic ester) of D-gluconic acid. D-(+)-Glucono-1,5-lactone is commonly found in honey, fruit juices, personal lubricants, and wine. D-(+)-Glucono-1,5-lactone is neutral, but hydrolyses in water to gluconic acid which is acidic, adding a tangy taste to foods, though it has roughly a third of the sourness of citric acid. It is metabolized to glucose; one gram of D-(+)-Glucono-1,5-lactone yields roughly the same amount of metabolicenergy as one gram of sugar. Upon addition to water, GDL is partially hydrolysed to gluconic acid, with the balance between the lactone form and the acid form established as a chemical equilibrium. The rate of hydrolysis of D-(+)-Glucono-1,5-lactone is increased by heat and high pH[1].
References

[1]. Xu Y, et al. Aggregation and structural changes of silver carp actomyosin as affected by mild acidification with D-gluconic acid δ-lactone. Food Chem. 2012 Sep 15;134(2):1005-10.

Density 0.6
Boiling Point 230.35°C
Melting Point 151-155 ºC
Molecular Formula C6H10O6
Molecular Weight 178.140
Flash Point 192.3±20.3 °C
Exact Mass 178.047745
PSA 107.22000
LogP -2.38
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.608
Water Solubility 500 g/L (20 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LZ5184000
CHEMICAL NAME :
Gluconic acid, delta-lactone, D-
CAS REGISTRY NUMBER :
90-80-2
LAST UPDATED :
199803
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C6-H10-O6
MOLECULAR WEIGHT :
178.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Microorganism - not otherwise specified
DOSE/DURATION :
5 mmol/L
REFERENCE :
AMICCW Archives of Microbiology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secacus, NJ 07094) V.95- 1974- Volume(issue)/page/year: 109,157,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80419 No. of Facilities: 3748 (estimated) No. of Industries: 25 No. of Occupations: 33 No. of Employees: 20328 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80419 No. of Facilities: 3645 (estimated) No. of Industries: 12 No. of Occupations: 28 No. of Employees: 184229 (estimated) No. of Female Employees: 157249 (estimated)
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn: Harmful;Xi: Irritant;
Risk Phrases R21
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS LZ5184000
HS Code 2932999099
HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%