- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Tirofiban hydrochloride
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Tirofiban hydrochloride
- Price: ￥798.0/10mg ￥3088.0/50mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: Tirofiban (hydrochloride monohydrate)
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Stocking Period: 1 Day
- Contact: Tony Lai
- DC Chemicals Limited
- China
- Product Name: Tirofiban (hydrochloride monohydrate)
- Price: $200.0/100mg $400.0/250mg $800.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Tirofiban hydrochloride monohydrate
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
150915-40-5
150915-40-5 structure
- Name: Tirofiban hydrochloride
- Chemical Name: tirofiban hydrochloride
- CAS Number: 150915-40-5
- Molecular Formula: C22H39ClN2O6S
- Molecular Weight: 495.073
- Catalog: API Circulatory system medication Prevention and treatment of angina pectoris
- Create Date: 2018-02-21 08:00:00
- Modify Date: 2024-01-02 09:12:15
-
Tirofiban hydrochloride monohydrate is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonistIC50 value:Target: integrin IIb/IIIa Tirofiban hydrochloride monohydrate blocks platelet aggregation and thrombus formation. Tirofiban is an antithrombotic used in the treatment of unstable angina.Tirofiban, in a concentration-dependent manner reduced platelet aggregation evoked by ADP (IC50 approximately 70 ng/ml), collagen (IC50 approximately 200 ng/ml), and thrombin (IC50 approximately 5,000 ng/ml).
| Name | tirofiban hydrochloride |
|---|---|
| Synonyms |
L 700462 MK 383 N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine
N-(butylsulfonyl)- O-[4-(4-piperidinyl)butyl]-L-tyrosine monohydrochloride monohydrate N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]tyrosine hydrochloride hydrate N-(Butylsulfonyl)-O-[4-(piperidin-4-yl)butyl]-L-tyrosine hydrochloride hydrate (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid,hydrate,hydrochloride Tirofiban hydrochloride Tirofiban hydrochloride monohydrate tirofiban hydrochloride anhydrous Tyrosine, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-, hydrochloride, hydrate (1:1:1) Tirofiban Hydrochloride Hydrate Tirofiban (hydrochloride monohydrate) |
| Description | Tirofiban hydrochloride monohydrate is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonistIC50 value:Target: integrin IIb/IIIa Tirofiban hydrochloride monohydrate blocks platelet aggregation and thrombus formation. Tirofiban is an antithrombotic used in the treatment of unstable angina.Tirofiban, in a concentration-dependent manner reduced platelet aggregation evoked by ADP (IC50 approximately 70 ng/ml), collagen (IC50 approximately 200 ng/ml), and thrombin (IC50 approximately 5,000 ng/ml). |
|---|---|
| Related Catalog | |
| References |
[4]. Valgimigli M, Tebaldi M. Safety evaluation of tirofiban. Expert Opin Drug Saf. 2010 Sep;9(5):801-19. |
| Boiling Point | 611.7ºC at 760 mmHg |
|---|---|
| Melting Point | 135-137ºC |
| Molecular Formula | C22H39ClN2O6S |
| Molecular Weight | 495.073 |
| Flash Point | 323.7ºC |
| Exact Mass | 494.221741 |
| PSA | 122.34000 |
| LogP | 5.48870 |
| Storage condition | -20°C Freezer |
| Water Solubility | DMSO: >12mg/mL at warmed to 60°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-37-45 |
| RIDADR | NONH for all modes of transport |