71079-09-9

71079-09-9 structure

Name: FOY 251-D4
Chemical Name: foy 251
CAS Number: 71079-09-9
Molecular Formula: C₁₇H₁₉N₃O₇S
Molecular Weight: 409.41400
Catalog: Research Areas Metabolic Disease
Create Date: 2017-05-05 19:56:40
Modify Date: 2024-01-15 12:35:09
FOY 251 is an anti-proteolytic active metabolite camostate (HY-13512), acts as a proteinase inhibitor[1].

Name	foy 251
Synonyms	4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]-benzeneacetic Acid Monomethanesulfonate 4-(4-guanidinobenzoyloxy)phenylacetic acid 4-(4-guanidinobenzoyloxy)phenylacetic acid mesylate 4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]-benzeneacetic Acid Monomethanesulfonat p-(p-Guanidinbenzoyloxy)-phenylessigsaeure-methansulfonat p-(p-guanidinobenzoyloxy)phenylacetic acid methanesulphonate

Description	FOY 251 is an anti-proteolytic active metabolite camostate (HY-13512), acts as a proteinase inhibitor[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	proteinase[1]
In Vitro	FOY-251 represents a dose-dependent inhibition of equivalent current in M-1 cells[2]. FOY-251 inhibits the proteolytic activity of prostasin[2].
References	[1]. K Beckh, et al. Elimination of the Low-Molecular Weight Proteinase Inhibitor Camostate (FOY 305) and Its Degradation Products by the Rat Liver. Res Exp Med (Berl). 1987;187(6):401-6. [2]. Ai Maekawa, et al. Camostat Mesilate Inhibits Prostasin Activity and Reduces Blood Pressure and Renal Injury in Salt-Sensitive Hypertension. J Hypertens . 2009 Jan;27(1):181-9.