4602-84-0

4602-84-0 structure

Name: farnesol
Chemical Name: farnesol
CAS Number: 4602-84-0
Molecular Formula: C₁₅H₂₆O
Molecular Weight: 222.366
Catalog: Organic raw materials Alcohols, phenols, phenolic compounds and derivatives Acyclic alcohol
Create Date: 2018-03-13 08:00:00
Modify Date: 2024-01-03 17:27:28
Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans, and has the activity in inhibiting bacteria.

Name	farnesol
Synonyms	(2-trans,6-trans)-farnesol (E,E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol Stirrup-TPW Stirrup-HB (2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trien-1-ol trans,trans-3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol (2E,6E)-Farnesol all-trans-farnesol all-E-Farnesol Farnesoi EINECS 225-004-1 MFCD00002918 farnesyl bromide 2,6,10-Dodecatrien-1-ol, 3,7,11-trimethyl-, (E,E)- (2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol trans,trans-Farnesol 2,6,10-Dodecatrien-1-ol, 3,7,11-trimethyl-, (2E,6E)- 3,7,10-trimethyl-2,6,10-dodecatrien-1-ol ALL TRANS FARNESOL FARNESOLP trans-Farnesol Farnesol,(E,E) 3,7,11-Trimethyl-2,6,10-dodecatrienol (E)-farnesol farnesyl alcohol (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol 3,7,11-Trimethyl-2,6,10-Dodecatrien-1-ol E,E-farnesol Stirrup-CRW Polyprenol Stirrup-H Farnesol (E,E)-Farnesol 3,7,11-Trimethyldodeca-2,6,10-trien-1-ol 3,7,11-Trimethyldodeca-2-trans,6-trans,10-trien-1-ol fci119a Inhibitor A2

Description	Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans, and has the activity in inhibiting bacteria.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection Natural Products >> Terpenoids and Glycosides
Target	Human Endogenous Metabolite
In Vitro	Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans. It is also shown that this molecule presents inhibitory effects against non-albicans Candida species, Paracoccidioides brasiliensis and bacteria. The minimum inhibitory concentrations (MICs) are determined in accordance with the M27-A3 protocol as described and Farnesol is tested at a concentration range of 0.29-150 μM. It is observed that Farnesol presents an inhibitory activity against C. neoformans and C. gattii (MIC range: 0.29-75.0 μM). Although Farnesol does not significantly alter phospholipase activity, a tendency to decrease this activity is observed[1].
References	[1]. Cordeiro Rde A, et al. Farnesol inhibits in vitro growth of the Cryptococcus neoformans species complex with no significant changes in virulence-related exoenzymes. Vet Microbiol. 2012 Oct 12;159(3-4):375-80.

Density	0.9±0.1 g/cm3
Boiling Point	283.4±0.0 °C at 760 mmHg
Molecular Formula	C₁₅H₂₆O
Molecular Weight	222.366
Flash Point	96.1±0.0 °C
Exact Mass	222.198364
PSA	20.23000
LogP	5.31
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.485
Storage condition	−20°C
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - antipsychotic

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - antipsychotic

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - antipsychotic

REFERENCE :: ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 43,1285,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5190 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 1557 (estimated) No. of Female Employees: 276 (estimated)

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H315-H317-H319-H411
Precautionary Statements	P273-P280-P333 + P313-P337 + P313-P391-P501
Personal Protective Equipment	Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes	Xi: Irritant;
Risk Phrases	R24/25
Safety Phrases	S22-S24/25
RIDADR	UN 3082 9 / PGIII
WGK Germany	3
RTECS	JR4979000
HS Code	2905290000

HS Code	2905290000
Summary	2905290000 unsaturated monohydric alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%