2276-93-9

2276-93-9 structure

Name: Isoallolithocholic acid
Chemical Name: (4R)-4-[(3S,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
CAS Number: 2276-93-9
Molecular Formula: C₂₄H₄₀O₃
Molecular Weight: 376.57300
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
Create Date: 2017-03-09 19:47:20
Modify Date: 2024-01-14 11:56:06
Alloisolithocholic acid (AILCA) activates large-conductance calcium-activated potassium (BK) channels with an EC50 value of 44.21 μM in Xenopus oocytes[1].

Name	(4R)-4-[(3S,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
Synonyms	lithocholic acid Isoallolithocholate 3b-Hydroxy-5a-cholanate Isoallolithocholic acid 3b-Hydroxy-5a-cholanoate Alloisolithocholic acid 3b-hydroxy-5a-cholan-24-oic acid Isolithocholic acid

Description	Alloisolithocholic acid (AILCA) activates large-conductance calcium-activated potassium (BK) channels with an EC50 value of 44.21 μM in Xenopus oocytes[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
References	[1]. Bukiya AN, et al. Structural determinants of monohydroxylated bile acids to activate beta 1 subunit-containing BK channels. J Lipid Res. 2008 Nov;49(11):2441-51.