27430-18-8
27430-18-8 structure
- Name: 4,6(1H,5H)-Pyrimidinedione,5-(2-furanylmethylene)dihydro-2-thioxo-
- Chemical Name: 5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione
- CAS Number: 27430-18-8
- Molecular Formula: C9H6N2O3S
- Molecular Weight: 222.22
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
- Create Date: 2018-11-28 22:13:50
- Modify Date: 2024-01-30 18:07:00
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CD00509 is a Tdp1 inhibitor, with an IC50 value of 0.71 μM. CD00509 can sensitize breast cancer cells to Camptothecin (HY-16560). CD00509 has anti-tumor activity[1].
| Name | 5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione |
|---|---|
| Synonyms |
5-(2-furylmethylene)-2-thioxo-1,3-dihydropyrimidine-4,6-dione
5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione 5-furan-2-ylmethylene-2-thioxodihydropyrimidine-4,6-dione 5-furfurylidene-2-thio-barbituric acid 5-Furfuryliden-2-thio-barbitursaeure 5-furfurylidene-2-thioxo-dihydro-pyrimidine-4,6-dione 5-(furan-2'-ylmethylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione |
| Description | CD00509 is a Tdp1 inhibitor, with an IC50 value of 0.71 μM. CD00509 can sensitize breast cancer cells to Camptothecin (HY-16560). CD00509 has anti-tumor activity[1]. |
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| Related Catalog | |
| References |
| Density | 1.54g/cm3 |
|---|---|
| Molecular Formula | C9H6N2O3S |
| Molecular Weight | 222.22 |
| Exact Mass | 222.01000 |
| PSA | 103.43000 |
| LogP | 0.85150 |
| Index of Refraction | 1.685 |
| HS Code | 2934999090 |
|---|
|
~92%
27430-18-8 |
| Literature: Paasz, Aleksandra Synthesis, 2010 , # 23 art. no. T12110SS, p. 4021 - 4032 |
|
~%
27430-18-8 |
| Literature: Dox; Plaisance Journal of the American Chemical Society, 1916 , vol. 38, p. 2165 |
| Precursor 3 | |
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| DownStream 0 | |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |