68-60-0

68-60-0 structure
68-60-0 structure
  • Name: Tetrahydro-11-deoxy Cortisol
  • Chemical Name: 1-[(3R,5R,8R,9S,10S,13S,14S,17R)-3,17-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-hydroxyethanone
  • CAS Number: 68-60-0
  • Molecular Formula: C21H34O4
  • Molecular Weight: 350.49200
  • Catalog: Research Areas Others
  • Create Date: 2018-10-08 07:03:23
  • Modify Date: 2024-01-16 11:17:42
  • Tetrahydro-11-deoxycortisol (Tetrahydrodeoxycortisol) is an endogenous metabolite present in Urine that can be used for the research of 11 Beta Hydroxylase Deficiency[1][2].

Name 1-[(3R,5R,8R,9S,10S,13S,14S,17R)-3,17-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-hydroxyethanone
Synonyms tetrahydrocortexolone
5beta-Pregnane-3alpha,17alpha,21-triol-20-one
3alpha,17alpha,21-Trihydroxy-5beta-pregnan-20-one
EINECS 200-691-0
Tetrahydrodeoxycortisol
Tetrahydro-11-deoxycortisol
Description Tetrahydro-11-deoxycortisol (Tetrahydrodeoxycortisol) is an endogenous metabolite present in Urine that can be used for the research of 11 Beta Hydroxylase Deficiency[1][2].
Related Catalog
In Vitro Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
References

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.  

[2]. Burren CP, et al. CYP11 beta 1 (11-beta-hydroxylase) deficiency in congenital adrenal hyperplasia. J Paediatr Child Health. 1996 Oct;32(5):433-8.  

Density 1.186g/cm3
Boiling Point 505.1ºC at 760 mmHg
Molecular Formula C21H34O4
Molecular Weight 350.49200
Flash Point 273.4ºC
Exact Mass 350.24600
PSA 77.76000
LogP 2.68250
Index of Refraction 1.56
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
Precursor  0

DownStream  2