55487-63-3

55487-63-3 structure

Name: Deoxycorticosterone-d8
Chemical Name: 11-Deoxy Corticosterone-d8
CAS Number: 55487-63-3
Molecular Formula: C₂₁H₂₂D₈O₃
Molecular Weight: 338.510
Catalog: Research Areas Others
Create Date: 2018-05-31 08:00:00
Modify Date: 2024-01-09 11:49:55
Deoxycorticosterone-d8 is the deuterium labeled Deoxycorticosterone. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor[1][2].

Name	11-Deoxy Corticosterone-d8
Synonyms	Pregn-4-ene-3,20-dione-2,2,4,6,6,17,21,21-d, 21-hydroxy- 21-Hydroxy(2,2,4,6,6,17,21,21-H)pregn-4-ene-3,20-dione 4-pregnen-21-ol-3,20-dione-2,2,4,6,6,17alpha,21,21-d8

Description	Deoxycorticosterone-d8 is the deuterium labeled Deoxycorticosterone. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor[1][2].
Related Catalog	Research Areas >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. KAGAWA CM, et al. Action of new steroids in blocking effects of aldosterone and desoxycorticosterone on salt. Science. 1957 Nov 15;126(3281):1015-6.