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9007-43-6

9007-43-6 structure

9007-43-6 structure

Name: Cytochrome C
Chemical Name: Cytochrome C
CAS Number: 9007-43-6
Molecular Formula: C₄₂H₅₂FeN₈O₆S₂
Molecular Weight: 884.887
Catalog: Biochemical Enzymes and coenzymes
Create Date: 2018-05-16 08:00:00
Modify Date: 2024-01-02 02:17:43
Cytochrome C is a multi-functional enzyme involving in life and death decisions of the cell. Cytochrome C is essential in mitochondrial electron transport and intrinsic type II apoptosis[1].

Name	Cytochrome C
Synonyms	Cytochromert EINECS 232-700-9 myohematin Cytor-est 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis[1-[[2-amino-3-(methylamino)-3-oxopropyl]thio]ethyl]-3,8,13,17-tetramethyl-, iron(2+) salt (1:1) CYT-C Iron(2+) (1Z,6Z,12Z,17Z)-4,9-bis(1-{[2-amino-3-(methylamino)-3-oxopropyl]sulfanyl}ethyl)-15,19-bis(2-carboxyethyl)-5,10,14,20-tetramethyl-21,22,23,24-tetraazapentacyclo[16.2.1.1.1.1] tetracosa-1,3(24),4,6,8,10,12,14,16(22),17,19-undecaene-21,23-diide Cytomac P cytorest MFCD00130890

Description	Cytochrome C is a multi-functional enzyme involving in life and death decisions of the cell. Cytochrome C is essential in mitochondrial electron transport and intrinsic type II apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Metabolic Disease
In Vitro	哺乳动物 Cytochrome C 在健康状态下清除活性氧 (ROS)，在凋亡过程中与辅因子 p66Shc 产生 ROS，氧化心磷脂[1]。
References	[1]. Hüttemann M, et al. The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: From respiration to apoptosis. Mitochondrion. 2011 May;11(3):369-81.

Boiling Point	1323.5ºC at 760 mmHg
Melting Point	300ºC
Molecular Formula	C₄₂H₅₂FeN₈O₆S₂
Molecular Weight	884.887
Flash Point	754.2ºC
Exact Mass	884.280090
PSA	286.03000
LogP	3.85300
Storage condition	−20°C
Water Solubility	H2O: 10 mg/mL, clear, dark red-brown \| 100 g/L (20 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HA5365000

CHEMICAL NAME :: Cytochrome C

CAS REGISTRY NUMBER :: 9007-43-6

LAST UPDATED :: 199701

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 250 mg/kg

SEX/DURATION :: female 1-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 20 ug/plate

REFERENCE :: ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 45,327,1981

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;Xn: Harmful;
Risk Phrases	36/37/38-20/21/22
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	HA5365000
HS Code	3507909000

HS Code	3507909000