42024-98-6

42024-98-6 structure

Name: Mazaticol
Chemical Name: (6,6,9-trimethyl-9-azabicyclo[3.3.1]nonan-3-yl) 2-hydroxy-2,2-dithiophen-2-ylacetate
CAS Number: 42024-98-6
Molecular Formula: C₂₁H₂₇NO₃S₂
Molecular Weight: 405.57
Catalog: Signaling Pathways GPCR/G Protein mAChR
Create Date: 2018-06-18 11:46:22
Modify Date: 2024-01-20 13:30:36
Mazaticol is an anticholinergic agent. Mazaticol blocks the muscarinic acetylcholine receptors and cholinergic nerve activity. Mazaticol is a potent 3H-QNB and 3H-PZ binding inhibitor, can bind to the M2 receptors with high affinity. Mazaticol exhibits inhibitory effects on dopamine uptake in the striatal nerve terminal. Mazaticol can be used for parkinsonian syndrome research[1][2].

Name	(6,6,9-trimethyl-9-azabicyclo[3.3.1]nonan-3-yl) 2-hydroxy-2,2-dithiophen-2-ylacetate
Synonyms	Mazaticol (INN) 6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl hydroxy(dithiophen-2-yl)acetate Mazaticol

Description	Mazaticol is an anticholinergic agent. Mazaticol blocks the muscarinic acetylcholine receptors and cholinergic nerve activity. Mazaticol is a potent 3H-QNB and 3H-PZ binding inhibitor, can bind to the M2 receptors with high affinity. Mazaticol exhibits inhibitory effects on dopamine uptake in the striatal nerve terminal. Mazaticol can be used for parkinsonian syndrome research[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
References	[1]. Niimi Y, et al. Mazaticol for Treating Parkinson. 2020. [2]. Katayama S, et al. Effects of anticholinergic antiparkinsonian drugs on binding of muscarinic receptor subtypes in rat brain. Res Commun Chem Pathol Pharmacol. 1990;69(3):261-270.