187237-35-0

187237-35-0 structure

Name: 5-Aminolevulinic acid-d2 hydrochloride
Chemical Name: 5-aminolevulinic-2,2-d2 acid hcl
CAS Number: 187237-35-0
Molecular Formula: C₅H₈D₂ClNO₃
Molecular Weight: 169.60
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-05-14 08:00:00
Modify Date: 2024-01-09 11:06:48
5-Aminolevulinic acid-d2 (hydrochloride) is deuterium labeled 5-Aminolevulinic acid (hydrochloride).

Name	5-aminolevulinic-2,2-d2 acid hcl
Synonyms	5-Aminolevulinic-2,2-D2 AcidHCI 5-Aminolevulinic-2,2-D2 AcidCI 2,2-dideutero-5-aminolevulinic acid hydrochloride 5-AMinolevulinic-d2 Acid HCl

Description	5-Aminolevulinic acid-d2 (hydrochloride) is deuterium labeled 5-Aminolevulinic acid (hydrochloride).
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Autophagy >> Mitophagy Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Stummer, W., et al., Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol, 2006. 7(5): p. 392-401. [3]. Eyupoglu, I.Y., et al., Improving the extent of malignant glioma resection by dual intraoperative visualization approach. PLoS One, 2012. 7(9): p. e44885.