- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Carboxyebselen
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Huang
- DC Chemicals Limited
- China
- Product Name: Carboxyebselen
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: carboxyebselen
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
153871-75-1
153871-75-1 structure
- Name: carboxyebselen
- Chemical Name: 4-(3-oxo-1,2-benzoselenazol-2-yl)benzoic acid
- CAS Number: 153871-75-1
- Molecular Formula: C14H9NO3Se
- Molecular Weight: 318.18600
- Catalog: Signaling Pathways Immunology/Inflammation NO Synthase
- Create Date: 2017-11-07 18:23:00
- Modify Date: 2024-02-03 11:57:30
-
Carboxyebselen (HOOC-Ebs) is a potent and selective inhibitor of endothelial nitric oxide synthase (eNOS)[1].
| Name | 4-(3-oxo-1,2-benzoselenazol-2-yl)benzoic acid |
|---|---|
| Synonyms |
4-(3-Oxo-1,2-benzoselenazol-2(3H)-yl)benzoic acid
Carboxyebselen 4-(1,2-benzisoselenazol-3-(2H)-one-2-yl)benzoic acid Hooc-ebs Benzoic acid,4-(3-oxo-1,2-benzisoselenazol-2(3H)-yl) 2-(carboxyphenyl)-1,2-benzisoselenazol-3(2H)-one 4-(2,3-dihydro-3-oxo-1,2-benzisoselenazol-2-yl)benzoic acid |
| Description | Carboxyebselen (HOOC-Ebs) is a potent and selective inhibitor of endothelial nitric oxide synthase (eNOS)[1]. |
|---|---|
| Related Catalog | |
| In Vivo | Carboxyebselen (HOOC-Ebs), a derivative of Ebselen (Ebs) inhibits NOS present in enzymatic preparations from bovine endothelium, porcine cerebella, and murine spleen, however, it is both more potent and more selective for the constitutive endothelial NOS than Ebs. Unlike Ebs, HOOC-Ebs (0.1-30 microM) causes a concentration-dependent endothelium-independent relaxations of rings of rabbit aorta[1]. |
| References |
| Boiling Point | 531.5ºC at 760mmHg |
|---|---|
| Molecular Formula | C14H9NO3Se |
| Molecular Weight | 318.18600 |
| Flash Point | 275.3ºC |
| Exact Mass | 318.97500 |
| PSA | 59.30000 |
| LogP | 1.74590 |
| Vapour Pressure | 3.96E-12mmHg at 25°C |
