carboxyebselen structure
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Common Name | carboxyebselen | ||
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CAS Number | 153871-75-1 | Molecular Weight | 318.18600 | |
Density | N/A | Boiling Point | 531.5ºC at 760mmHg | |
Molecular Formula | C14H9NO3Se | Melting Point | N/A | |
MSDS | N/A | Flash Point | 275.3ºC |
Use of carboxyebselenCarboxyebselen (HOOC-Ebs) is a potent and selective inhibitor of endothelial nitric oxide synthase (eNOS)[1]. |
Name | 4-(3-oxo-1,2-benzoselenazol-2-yl)benzoic acid |
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Synonym | More Synonyms |
Description | Carboxyebselen (HOOC-Ebs) is a potent and selective inhibitor of endothelial nitric oxide synthase (eNOS)[1]. |
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Related Catalog | |
In Vivo | Carboxyebselen (HOOC-Ebs), a derivative of Ebselen (Ebs) inhibits NOS present in enzymatic preparations from bovine endothelium, porcine cerebella, and murine spleen, however, it is both more potent and more selective for the constitutive endothelial NOS than Ebs. Unlike Ebs, HOOC-Ebs (0.1-30 microM) causes a concentration-dependent endothelium-independent relaxations of rings of rabbit aorta[1]. |
References |
Boiling Point | 531.5ºC at 760mmHg |
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Molecular Formula | C14H9NO3Se |
Molecular Weight | 318.18600 |
Flash Point | 275.3ºC |
Exact Mass | 318.97500 |
PSA | 59.30000 |
LogP | 1.74590 |
Vapour Pressure | 3.96E-12mmHg at 25°C |
~96% carboxyebselen CAS#:153871-75-1 |
Literature: Mlochowski, Jacek; Kloc, Krystian; Syper, Ludwik; Inglot, Anna D.; Piasecki, Egbert Liebigs Annalen der Chemie, 1993 , # 12 p. 1239 - 1244 |
4-(3-Oxo-1,2-benzoselenazol-2(3H)-yl)benzoic acid |
Carboxyebselen |
4-(1,2-benzisoselenazol-3-(2H)-one-2-yl)benzoic acid |
Hooc-ebs |
Benzoic acid,4-(3-oxo-1,2-benzisoselenazol-2(3H)-yl) |
2-(carboxyphenyl)-1,2-benzisoselenazol-3(2H)-one |
4-(2,3-dihydro-3-oxo-1,2-benzisoselenazol-2-yl)benzoic acid |