179420-17-8
179420-17-8 structure
- Name: CJ-13610
- Chemical Name: 4-[3-[4-(2-methylimidazol-1-yl)phenyl]sulfanylphenyl]oxane-4-carboxamide
- CAS Number: 179420-17-8
- Molecular Formula: C22H23N3O2S
- Molecular Weight: 393.50200
- Catalog: Signaling Pathways Metabolic Enzyme/Protease 5-Lipoxygenase
- Create Date: 2017-07-01 06:27:09
- Modify Date: 2024-02-04 13:32:38
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CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC50 of about 70 nM[1]. PMNL: polymorphonuclear leukocytes; AA: arachidonic acid
| Name | 4-[3-[4-(2-methylimidazol-1-yl)phenyl]sulfanylphenyl]oxane-4-carboxamide |
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| Synonyms | Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide |
| Description | CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC50 of about 70 nM[1]. PMNL: polymorphonuclear leukocytes; AA: arachidonic acid |
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| References |
| Melting Point | 198 - 200 °C |
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| Molecular Formula | C22H23N3O2S |
| Molecular Weight | 393.50200 |
| Exact Mass | 393.15100 |
| PSA | 96.43000 |
| LogP | 5.01510 |
| Storage condition | 2-8°C |
| RIDADR | NONH for all modes of transport |
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