68353-24-2

68353-24-2 structure

Name: 1-Methyl-2-nonylquinolin-4(1H)-one
Chemical Name: 1-methyl-2-nonylquinolin-4-one
CAS Number: 68353-24-2
Molecular Formula: C₁₉H₂₇NO
Molecular Weight: 285.424
Catalog: Natural product Alkaloid
Create Date: 2017-12-18 17:02:07
Modify Date: 2024-01-11 09:41:25
1-Methyl-2-nonyl-4(1H)-quinolone, a quinolone alkaloid, is a potent and selective MAO-B (monoamine oxidase) inhibitor. 1-Methyl-2-nonyl-4(1H)-quinolone exhibites inhibitory activity on leukotriene biosynthesis, with an IC50 of 12.1 μM[1][2].

Name	1-methyl-2-nonylquinolin-4-one
Synonyms	1-Methyl-2-nonyl-4(1H)-quinolinone 4(1H)-Quinolinone, 1-methyl-2-nonyl- N-methyl-2-nonyl-4-quinolone 1-Methyl-2-nonyl-4(1H)-quinolone 1-Methyl-2-n-nonyl-4-chinolon 1-methyl-2-nonyl-1H-quinolin-4-one

Description	1-Methyl-2-nonyl-4(1H)-quinolone, a quinolone alkaloid, is a potent and selective MAO-B (monoamine oxidase) inhibitor. 1-Methyl-2-nonyl-4(1H)-quinolone exhibites inhibitory activity on leukotriene biosynthesis, with an IC50 of 12.1 μM[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
Target	MAO-B MAO-A
In Vitro	1-Methyl-2-nonyl-4(1H)-quinolone shows more potent inhibitory effects against MAO-B compared to MAO-A[1].
References	[1]. Han XH, et al. Quinolone alkaloids from evodiae fructus and their inhibitory effects on monoamine oxidase. Arch Pharm Res. 2007 Apr;30(4):397-401. [2]. Adams M, et al. Inhibition of leukotriene biosynthesis by quinolone alkaloids from the fruits of Evodia rutaecarpa. Planta Med. 2004 Oct;70(10):904-8.

Hazard Codes	Xi

55396-45-7

74-88-4

~10%

68353-24-2