575-03-1

575-03-1 structure

Name: 7-Hydroxy-4-(trifluoromethyl)coumarin
Chemical Name: 7-Hydroxy-4-(trifluoromethyl)coumarin
CAS Number: 575-03-1
Molecular Formula: C₁₀H₅F₃O₃
Molecular Weight: 230.140
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyran compound
Create Date: 2018-03-19 08:00:00
Modify Date: 2024-01-04 12:51:20
4-(Trifluoromethyl)umbelliferone is fluorescent probe substrate for rat hepatic cytochrome P450 enzymes[1].

Name	7-Hydroxy-4-(trifluoromethyl)coumarin
Synonyms	7-Hydroxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one 7-Hydroxy-4-(trifluoromethyl)-2H-chromen-2-one 7-hydroxy-4-(trifluoromethyl)chromen-2-one 2H-1-Benzopyran-2-one, 7-hydroxy-4-(trifluoromethyl)- MFCD00037578

Description	4-(Trifluoromethyl)umbelliferone is fluorescent probe substrate for rat hepatic cytochrome P450 enzymes[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Others
References	[1]. Renwick AB, et, al. Evaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymes. Xenobiotica. 2001 Dec;31(12):861-78.

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H300-H315-H319-H335
Precautionary Statements	P261-P264-P301 + P310-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T:Toxic;
Risk Phrases	R25;R36/37/38
Safety Phrases	S26-S36-S45
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
HS Code	2932209090

372-31-6

108-46-3

~99%

575-03-1

Literature: Wu, Jie; Diao, Tianning; Sun, Wei; Li, Yizhe Synthetic Communications, 2006 , vol. 36, # 20 p. 2949 - 2956

70961-05-6

108-46-3

575-03-1

Literature: Bulletin of the Chemical Society of Ethiopia, , vol. 24, # 2 p. 305 - 310

220001-53-6

575-03-1

Literature: Xenobiotica, , vol. 30, # 10 p. 955 - 969

575-04-2

575-03-1

Literature: Acta Pharmacologica Sinica, , vol. 34, # 11 p. 1437 - 1448

1407499-96-0

575-03-1

118290-05-4

Literature: Angewandte Chemie - International Edition, , vol. 51, # 37 p. 9344 - 9347 Angew. Chem., , vol. 124, # 37 p. 9478 - 9481,5

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%