1188263-51-5

1188263-51-5 structure

Name: Tizanidine-d4 (hydrochloride)
Chemical Name: 5-chloro-N-(4,4,5,5-tetradeuterio-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine,hydrochloride
CAS Number: 1188263-51-5
Molecular Formula: C₉H₅D₄Cl₂N₅S
Molecular Weight: 294.20
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2017-10-22 17:34:20
Modify Date: 2024-01-11 23:07:30
Tizanidine-d4 (hydrochloride) is deuterium labeled Tizanidine (hydrochloride).

Name	5-chloro-N-(4,4,5,5-tetradeuterio-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine,hydrochloride
Synonyms	Tizanidine-d4 Hydrochloride

Description	Tizanidine-d4 (hydrochloride) is deuterium labeled Tizanidine (hydrochloride).
Related Catalog	Research Areas >> Cancer Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Neurological Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Kamen L, et al. A practical overview of tizanidine use for spasticity secondary to multiple sclerosis, stroke, and spinal cord injury. Curr Med Res Opin. 2008 Feb;24(2):425-39.