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10310-21-1

10310-21-1 structure
10310-21-1 structure

Name 6-chloroguanine
Synonyms 2-Amino-6-Chloro-Purin
2-Amino-6-chloropurine
MFCD00075252
EINECS 233-686-7
6-Chloroguanine
9H-Purin-2-amine, 6-chloro-
6-Chloro-3H-purin-2-amine
2-AMINO-6-CHLORO-PURINE
Description 6-Chloroguanine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
In Vitro 2-Amino-6-chloropurine 是合成核苷酸类似物的前体,具有抗 Epstein-Barr 病毒 (EBV) 和人类疱疹病毒 6 (HHV-6) 的抗病毒活性。11.Qiu, Y.-L., Ksebati, MB, Ptak, RG, et al.(Z)-和 (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine 和-guanine。具有广谱抗病毒活性的新型核苷酸类似物 J.医学。化学 41(1) 10-23 (1998)
References

[1]. Qiu, Y.-L., Ksebati, MB, Ptak, RG, et al.(Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleotide analogues with a broad-spectrum antiviral activityJ. Med. Chem.41(1) 10-23 (1998).

Density 1.8±0.1 g/cm3
Boiling Point 315.2ºC at 760mmHg
Melting Point >300 °C(lit.)
Molecular Formula C5H4ClN5
Molecular Weight 169.57
Flash Point 144.4ºC
Exact Mass 169.015518
PSA 80.48000
LogP -0.03
Vapour Pressure 1.75E-15mmHg at 25°C
Index of Refraction 1.827
Storage condition Keep Cold
Water Solubility 1.7 g/L (20 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UO7502000
CHEMICAL NAME :
Purine, 2-amino-6-chloro-
CAS REGISTRY NUMBER :
10310-21-1
LAST UPDATED :
199206
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C5-H4-Cl-N5
MOLECULAR WEIGHT :
169.59

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
20 mg/L/24H
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 139,149,1984
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi,Xn
Risk Phrases R20/21/22
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS UO7502000
HS Code 2933990090

~68%

10310-21-1 structure

10310-21-1

Literature: Luo, Lei; Chen, Guorong; Li, Yuanchao Heterocycles, 2008 , vol. 75, # 11 p. 2803 - 2808

~85%

10310-21-1 structure

10310-21-1

Literature: Hu, Yu Lin; Ge, Qiang; Lu, Ming; Lu, Hong Fei Bulletin of the Chemical Society of Ethiopia, 2010 , vol. 24, # 3 p. 425 - 432

~86%

10310-21-1 structure

10310-21-1

Literature: Steklov, Mikhail Yu.; Tararov, Vitali I.; Romanov, Georgy A.; Mikhailov, Sergey N. Nucleosides, Nucleotides and Nucleic Acids, 2011 , vol. 30, # 7-8 p. 503 - 511

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10310-21-1 structure

10310-21-1

Literature: Journal of Heterocyclic Chemistry, , vol. 48, # 5 p. 1140 - 1144

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10310-21-1 structure

10310-21-1

Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 30, # 7-8 p. 503 - 511
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%