2004-07-1

2004-07-1 structure

Name: 6-Chloroguanineriboside
Chemical Name: 2-Amino-6-chloropurine-9-riboside
CAS Number: 2004-07-1
Molecular Formula: C₁₀H₁₂ClN₅O₄
Molecular Weight: 301.69
Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
Create Date: 2018-09-13 16:54:27
Modify Date: 2024-01-03 01:32:16
6-Chloroguanineriboside (6-Chloroguanosine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-Amino-6-chloropurine-9-riboside
Synonyms	(−)-2-Amino-6-chloropurine riboside 6-Chloroguanine riboside 6-Chloroguanineriboside 2-Amino-6-chloro-9-(β-D-ribofuranosyl)purine 6-Chloro-9-(β-D-ribofuranosyl)-9H-purin-2-amine EINECS 217-905-3 (−)-2-Amino-6-chloropurine riboside 6-CHLOROGUANOSINE 2-Amino-6-chloropurine Riboside 6-Chloroguanine nucleoside 6-CHLOROADENOSINE 6-Chloroguanosine2 MFCD00005735 2-Amino-6-chloropurine-9--D-riboside 9H-Purin-2-amine, 6-chloro-9-β-D-ribofuranosyl- 6-Chloroguanine riboside 2-amino-6-chloro purineriboside

Description	6-Chloroguanineriboside (6-Chloroguanosine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3