29550-13-8

29550-13-8 structure

Name: Negletein
Chemical Name: 5,6-dihydroxy-7-methoxyflavone
CAS Number: 29550-13-8
Molecular Formula: C₁₆H₁₂O₅
Molecular Weight: 284.26300
Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
Create Date: 2018-05-30 08:00:00
Modify Date: 2024-01-09 13:11:21
Negletein is a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 and 10.8 μM, respectively[1].

Name	5,6-dihydroxy-7-methoxyflavone
Synonyms	BAICALEIN-7-METHYL ETHER 7-O-Methylbaicalein 5,6-dihydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one 5,6-dihydroxy-7-methoxy-2-phenyl-4H-chromen-4-one BAICALEIN METHYL ETHER NEGLETEIN 5,6-dihydroxy-7-methoxy-2-phenyl-chromen-4-one

Description	Negletein is a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 and 10.8 μM, respectively[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
References	[1]. Phan CW, et al. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Biofactors. 2016 Nov 12;42(6):591-599. [2]. Singh B, et al. Anti-inflammatory and immunomodulatory flavones from Actinocarya tibetica Benth.Nat Prod Res. 2013;27(23):2227-30.

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%