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15345-89-8

15345-89-8 structure
15345-89-8 structure
  • Name: Desmethoxyyangonin
  • Chemical Name: Desmethoxy Yangonin
  • CAS Number: 15345-89-8
  • Molecular Formula: C14H12O3
  • Molecular Weight: 228.243
  • Catalog: Natural product Phenols
  • Create Date: 2018-03-07 08:00:00
  • Modify Date: 2024-01-03 09:16:11
  • Desmethoxyyangonin is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.

Name Desmethoxy Yangonin
Synonyms DIHYDROKAVAIN
2H-Pyran-2-one, 4-methoxy-6-(2-phenylethenyl)-
2H-Pyran-2-one, 4-methoxy-6-[(E)-2-phenylethenyl]-
4-Methoxy-6-[(E)-2-phenylvinyl]-2H-pyran-2-one
4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one
Desmethoxyyangonin
(E)-4-Methoxy-6-(2-phenylethenyl)-2H-pyran-2-one,5,6-Dehydrokavain,Demethoxyyangonin
Density 1.2±0.1 g/cm3
Boiling Point 440.0±45.0 °C at 760 mmHg
Melting Point 138-140ºC
Molecular Formula C14H12O3
Molecular Weight 228.243
Flash Point 188.0±23.3 °C
Exact Mass 228.078644
PSA 39.44000
LogP 1.80
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.588
Storage condition 2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ1240000
CHEMICAL NAME :
2H-Pyran-2-one, 4-methoxy-6-styryl-, (E)-
CAS REGISTRY NUMBER :
15345-89-8
LAST UPDATED :
199206
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C14-H12-O3
MOLECULAR WEIGHT :
228.26
WISWESSER LINE NOTATION :
T6OVJ DO1 F1U1R DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 177,261,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 177,261,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
55 mg/kg
TOXIC EFFECTS :
Behavioral - anticonvulsant
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 177,261,1969
RIDADR NONH for all modes of transport