84104-71-2

84104-71-2 structure

Name: Wilforlide A
Chemical Name: wilforlide a
CAS Number: 84104-71-2
Molecular Formula: C₃₀H₄₆O₃
Molecular Weight: 454.684
Catalog: Natural product Moss
Create Date: 2018-06-11 17:06:11
Modify Date: 2024-01-02 08:57:32
Wilforlide A is a natural product, separated from the ethanolic extract of tripterygium wilfordii. IC50 value:Target:In vitro:In vivo: Carrageenan-induced rat pedal swelling, tampon-induced rat granulation, and mice ear inhibition rate of swelling trail results show that high-dose wilforlide A has obvious anti-inflammatory effect, but has no significant immune suppressive activity [1].

Name	wilforlide a
Synonyms	Olean-12-en-29-one, 22,29-epoxy-3-hydroxy-, (3β,22α)- WOLFORLIDE A (3β,22α)-3-Hydroxy-22,29-epoxyolean-12-en-29-one Regelide Wilforlide WilforlideA abruslactone A

Description	Wilforlide A is a natural product, separated from the ethanolic extract of tripterygium wilfordii. IC50 value:Target:In vitro:In vivo: Carrageenan-induced rat pedal swelling, tampon-induced rat granulation, and mice ear inhibition rate of swelling trail results show that high-dose wilforlide A has obvious anti-inflammatory effect, but has no significant immune suppressive activity [1].
Related Catalog	Signaling Pathways >> Others >> Others Natural Products >> Terpenoids and Glycosides Research Areas >> Inflammation/Immunology
References	[1]. Mei Xue, et al. Comparative study on the anti-inflammatory and immune suppressive effect of Wilforlide A. Fitoterapia Volume 81, Issue 8, December 2010, Pages 1109–1112 [2]. HU Jian-lin, et al. Determination of Wilforlide A in Tripterygium hypoglaucum (Levl.) Hutch by HPLC. Journal of Kunming Medical College, 2010-07

Hazard Codes	C

Precursor 0
DownStream 1
84108-17-8