10101-89-0

10101-89-0 structure

Name: Trisodium phosphate dodecahydrate
Chemical Name: Trisodium phosphate dodecahydrate
CAS Number: 10101-89-0
Molecular Formula: H₂₄Na₃₆O₁₆P
Molecular Weight: 380.18
Catalog: Inorganic chemical industry Inorganic salt Phosphides, metal phosphoric acid, metaphosphoric acid, hypophosphorous acid and pyrophosphate
Create Date: 2018-06-24 18:09:08
Modify Date: 2024-01-02 16:31:04
Trisodium phosphate dodecahydrate is a corrosion inhibitor for iron in 0.1 M NaClO4, in both aerated and deaerated solutions. Trisodium phosphate dodecahydrate can be used as an excipient, such as pH regulator, buffer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

Name	Trisodium phosphate dodecahydrate
Synonyms	trisodium,phosphate,dodecahydrate Sodium phosphate,tribasic dodecahydrate MFCD00149198 Sodium phosphate hydrate (3:1:12) Phosphoric acid, trisodium salt, dodecahydrate Trisodium phosphate dodecahydrate Sodium phosphate tribasic dodecahydrate EINECS 231-509-8 Phosphoric acid trisodium salt dodecahydrate Sodium phosphate dodecahydrate

Description	Trisodium phosphate dodecahydrate is a corrosion inhibitor for iron in 0.1 M NaClO4, in both aerated and deaerated solutions. Trisodium phosphate dodecahydrate can be used as an excipient, such as pH regulator, buffer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Armstrong R D, et al. Behaviour of sodium silicate and sodium phosphate (tribasic) as corrosion inhibitors for iron[J]. Journal of applied electrochemistry, 1994, 24: 1244-1248. [2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

Density	1.62
Boiling Point	158ºC at 760 mmHg
Melting Point	75 °C
Molecular Formula	H₂₄Na₃₆O₁₆P
Molecular Weight	380.18
Exact Mass	380.049500
PSA	206.82000
Index of Refraction	1.4458
Storage condition	Store at RT.
Stability	Stable. Incompatible with strong acids. Keep dry.
Water Solubility	258 g/L (20 ºC)

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. (Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV. Volume(issue)/page/year: 257,791,1963 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T1585 No. of Facilities: 154 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 308 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1585 No. of Facilities: 3662 (estimated) No. of Industries: 36 No. of Occupations: 31 No. of Employees: 31308 (estimated) No. of Female Employees: 6999 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	C:Corrosive
Risk Phrases	R35
Safety Phrases	S26-S36/37/39-S45
RIDADR	UN 3262 8/PG 3
WGK Germany	1
RTECS	TC9575000
Packaging Group	III
Hazard Class	8
HS Code	2835291000

HS Code	2835291000