65189-70-0

65189-70-0 structure

Name: H1-7 acetate salt
Chemical Name: 1-[2-[[2-[2-[[6-amino-2-[[2-[[2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]propanoylamino]-3-hydroxypropanoyl]amino]acetyl]pyrrolidine-2-carboxylic acid
CAS Number: 65189-70-0
Molecular Formula: C₃₁H₅₈N₁₄O₉
Molecular Weight: 770.88100
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK PKA
Create Date: 2016-07-25 04:21:02
Modify Date: 2024-01-14 07:57:32
H1-7 (histone H1 phosphorylation site), PKA Substrate, a synthetic polypeptide, can be used as PKA substrate[1][2].

Name	1-[2-[[2-[2-[[6-amino-2-[[2-[[2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]propanoylamino]-3-hydroxypropanoyl]amino]acetyl]pyrrolidine-2-carboxylic acid
Synonyms	HISTONE H1 PHOSPHORYLATION SITE Histone-7 Cyclic-AMP dependent protein kinase substrate ARG-ARG-LYS-ALA-SER-GLY-PRO 1-{2-[2-(2-{6-amino-2-[2-(2-amino-5-carbamimidamidopentanamido)-5-carbamimidamidopentanamido]hexanamido}propanamido)-3-hydroxypropanamido]acetyl}pyrrolidine-2-carboxylic acid H1-7 (histone H1 phosphorylation site),PKA Substrate Arg-Arg-Lys-Ala-Ser-Gly-Pro-OH ARG-ARG-LYS-ALA-SER-GLY-PRO: RRKASGP RRKASGP

Description	H1-7 (histone H1 phosphorylation site), PKA Substrate, a synthetic polypeptide, can be used as PKA substrate[1][2].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PKA Research Areas >> Others Signaling Pathways >> Stem Cell/Wnt >> PKA
In Vitro	H1-7 (histone H1 phosphorylation site), PKA Substrate可用于检测 PKA 活性[2]。
References	[1]. Pomerantz AH, et, al. Studies on the mechanism of phosphorylation of synthetic polypeptides by a calf thymus cyclic AMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1977 Oct;74(10):4261-5. [2]. Arif A, et, al. EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice. Nature. 2017 Feb 16;542(7641):357-361.