Name | darunavir |
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Synonyms |
(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](isobutyl)amino}-3-hydroxy-1-phenyl-2-butanyl]carbamate
Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester Darunavir TMC-114 (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](isobutyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate |
Description | Darunavir(TMC114) is an HIV protease inhibitor.IC50 Value: Target: HIV ProteaseDarunavir HIV-1 antiviral structurally is similar to amprenavir and it is second generation HIV-1-protease inhibitor. Darunavir is a drug used to treat HIV infection. It is in the protease inhibitor class. Prezista is an OARAC recommended treatment option for treatment-naive and treatment-experienced adults and adolescents. |
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Related Catalog |
Density | 1.3±0.1 g/cm3 |
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Melting Point | 74-76ºC |
Molecular Formula | C27H37N3O7S |
Molecular Weight | 547.664 |
Exact Mass | 547.235229 |
PSA | 148.80000 |
LogP | 3.94 |
Index of Refraction | 1.620 |
Storage condition | -20°C Freezer |
Hazard Codes | Xi |
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RIDADR | NONH for all modes of transport |