120638-55-3

120638-55-3 structure

Name: bromfenac sodium salt sesquihydrate
Chemical Name: bromfenac sodium salt sesquihydrate
CAS Number: 120638-55-3
Molecular Formula: C₁₅H₁₂BrNO_3.3/₂H₂O_.Na
Molecular Weight: 383.17
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-07-16 19:03:11
Modify Date: 2024-01-03 15:17:20
Bromfenac (sodium hydrate) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity(1) Bromfenac (sodium hydrate) (1 mg/kg, i.v.) is metabolited into an unusual conjugate, bromfenac N-glucoside, in rats bile(2) Bromfenac (sodium hydrate) permeation was found to be 1.62-fold higher through ChS-CS-NPs

Name	bromfenac sodium salt sesquihydrate
Synonyms	Sodium (2-amino-3-(4-bromobenzoyl)phenyl)acetate bromfenacum [INN_la] Bromfenac monosodium salt sesquihydrate Unii-8ecv571Y37 [2-Amino-3-(4-bromobenzoyl)phenyl]acetic acid BroMfenac sodiuM 1.5H2O Bromfenac Sodium Sesquihydrate Bromfenac ophthalmic Bromfenac ophthalmic solution Benzeneacetic acid, 2-amino-3-(4-bromobenzoyl)- bromfenac Bromfenac sodium Duract Bromfenac (sodium hydrate)

Description	Bromfenac (sodium hydrate) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity(1) Bromfenac (sodium hydrate) (1 mg/kg, i.v.) is metabolited into an unusual conjugate, bromfenac N-glucoside, in rats bile(2) Bromfenac (sodium hydrate) permeation was found to be 1.62-fold higher through ChS-CS-NPs
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Kirkman SK et al. Isolation and identification of bromfenac glucoside from rat bile. Drug Metab Dispos. 1998 Jul;26(7):720-3. [2]. Abdullah TA et al. Chondroitin sulfate-chitosan nanoparticles for ocular delivery of bromfenac sodium: Improved permeation, retention, and penetration. Int J Pharm Investig. 2016 Apr-Jun;6(2):96-105.