22203-98-1
22203-98-1 structure
- Name: Benzamide,5-chloro-N-(3-chlorophenyl)-2-hydroxy-
- Chemical Name: 5-chloro-N-(3-chlorophenyl)-2-hydroxybenzamide
- CAS Number: 22203-98-1
- Molecular Formula: C13H9Cl2NO2
- Molecular Weight: 282.12
- Catalog: Signaling Pathways Anti-infection SARS-CoV
- Create Date: 2017-04-19 18:44:41
- Modify Date: 2024-02-13 02:56:02
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SARS-CoV-2-IN-14 (compound 6) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.39 μM. SARS-CoV-2-IN-14 is a niclosamide analogue. SARS-CoV-2-IN-14 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally[1].
| Name | 5-chloro-N-(3-chlorophenyl)-2-hydroxybenzamide |
|---|---|
| Synonyms | 3',5-dichlorosalicylanilide |
| Description | SARS-CoV-2-IN-14 (compound 6) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.39 μM. SARS-CoV-2-IN-14 is a niclosamide analogue. SARS-CoV-2-IN-14 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally[1]. |
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| Related Catalog | |
| References |
| Density | 1.479g/cm3 |
|---|---|
| Boiling Point | 361.5ºC at 760 mmHg |
| Molecular Formula | C13H9Cl2NO2 |
| Molecular Weight | 282.12 |
| Flash Point | 172.4ºC |
| Exact Mass | 281.00100 |
| PSA | 49.33000 |
| LogP | 4.02430 |
| Vapour Pressure | 9.91E-06mmHg at 25°C |
| Index of Refraction | 1.685 |
| Storage condition | 2-8°C |
| Hazard Codes | Xn |
|---|---|
| HS Code | 2924299090 |
|
~87%
22203-98-1 |
| Literature: Imramovsky, Ales; Vinsova, Jarmila; Ferriz, Juana Monreal; Kunes, Jiri; Pour, Milan; Dolezal, Martin Tetrahedron Letters, 2006 , vol. 47, # 29 p. 5007 - 5011 |
| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |