14259-58-6
14259-58-6 structure
- Name: 5'-Deoxy-5'-iodouridine
- Chemical Name: 1-[(2R,3R,4S,5S)-3,4-dihydroxy-5-(iodomethyl)oxolan-2-yl]pyrimidine-2,4-dione
- CAS Number: 14259-58-6
- Molecular Formula: C9H11IN2O5
- Molecular Weight: 354.10
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2017-03-21 06:24:35
- Modify Date: 2024-01-11 20:14:50
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5'-Deoxy-5'-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 1-[(2R,3R,4S,5S)-3,4-dihydroxy-5-(iodomethyl)oxolan-2-yl]pyrimidine-2,4-dione |
|---|---|
| Synonyms |
5'-iodo-5'-deoxy-uridine
5'-Jod-5'-desoxy-uridin Uridine,5'-deoxy-5'-iodo 5'-Iodo-2'deoxyuridine 5'-deoxy-5'-iodouridine |
| Description | 5'-Deoxy-5'-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 2.118g/cm3 |
|---|---|
| Molecular Formula | C9H11IN2O5 |
| Molecular Weight | 354.10 |
| Exact Mass | 353.97100 |
| PSA | 104.81000 |
| Index of Refraction | 1.694 |
| Hazard Codes | Xn |
|---|
|
~86%
14259-58-6 |
| Literature: F. HOFFMANN-LA ROCHE AG Patent: WO2005/864 A1, 2005 ; Location in patent: Page 23 ; |
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~%
14259-58-6 |
| Literature: Devos, Rene Robert; Hobbs, Christopher John; Jiang, Wen Rong; Martin, Joseph Armstrong; Merrett, John Herbert; Najera, Isabel; Shimma, Nobuo; Tsukuda, Takuo Patent: US2003/236216 A1, 2003 ; Location in patent: Page 20 ; |
| Precursor 2 | |
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| DownStream 0 | |