302912-05-6

302912-05-6 structure

Name: 1,4-Bis[(2H)sulfanyl]-2,3-(2H6)butane(2H2)diol
Chemical Name: 1,1,2,3,4,4-hexadeuterio-2,3-dideuteriooxy-1,4-bis(deuteriosulfanyl)butane
CAS Number: 302912-05-6
Molecular Formula: C₄D₁₀O₂S₂
Molecular Weight: 164.313
Catalog: Research Areas Others
Create Date: 2018-02-18 08:00:00
Modify Date: 2024-01-02 08:33:34
DL-dithiothreitol-d10 is the deuterium labeled DL-dithiothreitol[1]. DL-dithiothreitol (DTT) is a reducing agent. DL-dithiothreitol forms a stable six-membered ring with an internal disulfide bond once oxidized[2].

Name	1,1,2,3,4,4-hexadeuterio-2,3-dideuteriooxy-1,4-bis(deuteriosulfanyl)butane
Synonyms	DL-Dithiothreitol-d10 Cleland's reagent-d10 1,4-Bis[(H)sulfanyl]-2,3-(H)butane(H)diol 2,3-Butane-1,1,2,3,4,4-d-diol-d, 1,4-di(mercapto-d)- Cleland inverted exclamation mark s reagent-d10 MFCD00190434

Description	DL-dithiothreitol-d10 is the deuterium labeled DL-dithiothreitol[1]. DL-dithiothreitol (DTT) is a reducing agent. DL-dithiothreitol forms a stable six-membered ring with an internal disulfide bond once oxidized[2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Dithiothreitol, From Wikipedia

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Hazard Codes	Xn: Harmful;
Risk Phrases	22-36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport