195156-77-5

195156-77-5 structure
195156-77-5 structure
  • Name: ValoMaciclovir Stearate
  • Chemical Name: [(2R)-4-[(2S)-2-amino-3-methylbutanoyl]oxy-2-[(2-amino-6-oxo-3H-purin-9-yl)methyl]butyl] octadecanoate
  • CAS Number: 195156-77-5
  • Molecular Formula: C33H58N6O5
  • Molecular Weight: 618.85100
  • Catalog: Signaling Pathways Anti-infection HSV
  • Create Date: 2016-09-20 11:11:20
  • Modify Date: 2024-01-12 01:14:49
  • Valomaciclovir stearate (ABT 606), a nucleoside analog, is the Omaciclovir (HY-116174) prodrug. Valomaciclovir stearate has antiviral activity against HSV-1 and varicella zoster virus (VZV)[1].

Name [(2R)-4-[(2S)-2-amino-3-methylbutanoyl]oxy-2-[(2-amino-6-oxo-3H-purin-9-yl)methyl]butyl] octadecanoate
Synonyms valomaciclovir
(R)-9-[2-(octadecanoyloxymethyl)-4-(L-valyloxy)butyl]guanine
L-valine (3R)-3-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methyl]-4-[(1-oxooctadecyl)oxy]butyl ester
ABT 606
(R)-9-[2-(stearoyloxymethyl)-4-(L-valyloxy)butyl]guanine
Valomaciclovir stearate
Valomaciclovir stearate [USAN]
Description Valomaciclovir stearate (ABT 606), a nucleoside analog, is the Omaciclovir (HY-116174) prodrug. Valomaciclovir stearate has antiviral activity against HSV-1 and varicella zoster virus (VZV)[1].
Related Catalog
References

[1]. Birkmann A, et al. Drugs in development for herpes simplex and varicella zoster virus. Clin Pharmacol Ther. 2017 Jul;102(1):30-32.  

Density 1.17g/cm3
Boiling Point 758.3ºC at 760 mmHg
Molecular Formula C33H58N6O5
Molecular Weight 618.85100
Flash Point 412.4ºC
Exact Mass 618.44700
PSA 169.20000
LogP 7.08200
Vapour Pressure 6.83E-23mmHg at 25°C
Index of Refraction 1.564

~%

195156-77-5 structure

195156-77-5

Literature: Mediver AB Patent: US6184376 B2, 2001 ;

~%

195156-77-5 structure

195156-77-5

Literature: Mediver AB Patent: US6184376 B2, 2001 ;