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572-59-8

572-59-8 structure
572-59-8 structure

Name (R)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol
Synonyms GNF-Pf-180
9-epi-Quinidine
Epiquinidine
Description Epiquinidine, a quinine analogue, can be used as the ggTas2r1 agonist. Epiquinidine activates ggTas2r1 at or beyond 10 µM[1].
Related Catalog
Target

ggTas2r1[1]

References

[1]. Pizio AD, et, al. Ligand binding modes from low resolution GPCR models and mutagenesis: chicken bitter taste receptor as a test-case. Sci Rep. 2017 Aug 15;7(1):8223.

Density 1.218g/cm3
Boiling Point 495.88ºC at 760 mmHg
Melting Point 111-113°
Molecular Formula C20H24N2O2
Molecular Weight 324.41700
Flash Point 253.699ºC
Exact Mass 324.18400
PSA 45.59000
LogP 3.11110
Index of Refraction 1.638
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger
Hazard Statements H302-H317-H334
Precautionary Statements P261-P280-P342 + P311
Hazard Codes Xn
Risk Phrases 22-42/43
Safety Phrases 22-36/37-45
RIDADR NONH for all modes of transport