3778-29-8

3778-29-8 structure

Name: 6-Hydroxykynurenic acid
Chemical Name: 6-hydroxy-4-oxo-1H-quinoline-2-carboxylic acid
CAS Number: 3778-29-8
Molecular Formula: C₁₀H₇NO₄
Molecular Weight: 205.16700
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2017-09-30 01:36:16
Modify Date: 2024-01-05 18:55:25
6-Hydroxykynurenic acid (6-HKA) is a derivative of kynurenic acid (KYNA) and can be isolated from Ginkgo leaves. 6-Hydroxykynurenic acid is a low-affinity NMDAR antagonist (IC50: 59 μM)[1].

Name	6-hydroxy-4-oxo-1H-quinoline-2-carboxylic acid
Synonyms	6-Hydroxykynurenic acid 4,6-dihydroxy-2-carboxyquinoline 6-Hydroxykynureninsaeure 4,6-dihydroxy-quinoline-2-carboxylic acid Quinaldic acid,4,6-dihydroxy 6-Hydroxykynurensaeure 6-Hydroxykynurenate 4,6-Dihydroxyquinaldic acid 4,6-Dihydroxy-chinolin-2-carbonsaeure

Description	6-Hydroxykynurenic acid (6-HKA) is a derivative of kynurenic acid (KYNA) and can be isolated from Ginkgo leaves. 6-Hydroxykynurenic acid is a low-affinity NMDAR antagonist (IC50: 59 μM)[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
Target	IC50: 59 μM (NMDAR)[1]
References	[1]. Weber M, et al. 6-Hydroxykynurenic acid and kynurenic acid differently antagonise AMPA and NMDA receptors in hippocampal neurones. J Neurochem. 2001 May;77(4):1108-15.

HS Code	2933499090

Precursor 0
DownStream 1
3517-61-1

HS Code	2933499090
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%