287100-69-0

287100-69-0 structure
287100-69-0 structure

Name (2R,3S,4R,5R)-hexane-1,2,3,4,5,6-hexol
Synonyms D-Mannitol-2-13C
Description D-Mannitol-2-13C is the 13C labeled D-Mannitol.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Tan, K., et al., The mannitol operon repressor MtlR belongs to a new class of transcription regulators in bacteria. J Biol Chem, 2009. 284(52): p. 36670-9.;Nishiyama, A., et al., Mannitol lowers fat digestibility and body fat accumulation in both normal a

Melting Point 167-170ºC(lit.)
Molecular Formula C6H14O6
Molecular Weight 183.16400
Exact Mass 183.08200
PSA 121.38000
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport