287112-34-9

287112-34-9 structure

Name: D-Mannitol-13C6
Chemical Name: d-[ul-13c6]mannitol
CAS Number: 287112-34-9
Molecular Formula: C₆H₁₄O₆
Molecular Weight: 188.12800
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2016-04-10 10:44:46
Modify Date: 2024-01-11 10:07:43
D-Mannitol-13C6 is the 13C labeled D-Mannitol[1]. D-Mannitol is an osmotic diuretic agent and a weak renal vasodilator[2][3][4].

Name	d-[ul-13c6]mannitol

Description	D-Mannitol-13C6 is the 13C labeled D-Mannitol[1]. D-Mannitol is an osmotic diuretic agent and a weak renal vasodilator[2][3][4].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Tan, K., et al., The mannitol operon repressor MtlR belongs to a new class of transcription regulators in bacteria. J Biol Chem, 2009. 284(52): p. 36670-9. [3]. Nishiyama, A., et al., Mannitol lowers fat digestibility and body fat accumulation in both normal and cecectomized rats. J Nutr Sci Vitaminol (Tokyo), 2009. 55(3): p. 242-51. [4]. Hanieh, H. and E. Sakaguchi, Effect of D-mannitol on feed digestion and cecotrophic system in rabbits. Anim Sci J, 2009. 80(2): p. 157-62.