Name | (+)-sesamin |
---|---|
Synonyms |
Sesamin
(7S,7’S,8R,8’R)-sesamin 5,5'-(1S,3aR,4S,6aR)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diylbis(1,3-benzodioxole) (+)-Sesamin Pseudocubebin d-Sesamin SesameP.E. SezaMin 1,3-Benzodioxole, 5,5'-[(1S,3aR,4S,6aR)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis- FAGAROL |
Description | Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2]. |
---|---|
Related Catalog | |
Target |
delta 5 desaturase[1] |
In Vitro | Pretreated with sesamin, Excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells was significantly attenuated[1]. |
In Vivo | Sesamin (o.p.; 20 mg/kg/day) significantly reduces the infarct size by approximately 50% in male gerbils (60-85 g)[1]. |
References |
Density | 1.4±0.1 g/cm3 |
---|---|
Boiling Point | 504.4±50.0 °C at 760 mmHg |
Melting Point | 122-124ºC |
Molecular Formula | C20H18O6 |
Molecular Weight | 354.353 |
Flash Point | 212.3±30.0 °C |
Exact Mass | 354.110352 |
PSA | 55.38000 |
LogP | 3.32 |
Vapour Pressure | 0.0±1.2 mmHg at 25°C |
Index of Refraction | 1.623 |
Storage condition | −20°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
---|---|
Hazard Codes | Xi |
Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2932999099 |
HS Code | 2932999099 |
---|---|
Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |