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  • BioBioPha
  • China
  • Product Name: Sesamin
  • Price: ¥Inquiry/5mg
  • Purity: 98.0%
  • Stocking Period: 10 Day
  • Contact: Xueping-Zheng



607-80-7

607-80-7 structure
607-80-7 structure
  • Name: Sesamin
  • Chemical Name: (+)-sesamin
  • CAS Number: 607-80-7
  • Molecular Formula: C20H18O6
  • Molecular Weight: 354.353
  • Catalog: Biochemical Natural product
  • Create Date: 2018-07-04 11:29:41
  • Modify Date: 2024-01-09 17:51:21
  • Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2].

Name (+)-sesamin
Synonyms Sesamin
(7S,7’S,8R,8’R)-sesamin
5,5'-(1S,3aR,4S,6aR)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diylbis(1,3-benzodioxole)
(+)-Sesamin
Pseudocubebin
d-Sesamin
SesameP.E.
SezaMin
1,3-Benzodioxole, 5,5'-[(1S,3aR,4S,6aR)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis-
FAGAROL
Description Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2].
Related Catalog
Target

delta 5 desaturase[1]

In Vitro Pretreated with sesamin, Excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells was significantly attenuated[1].
In Vivo Sesamin (o.p.; 20 mg/kg/day) significantly reduces the infarct size by approximately 50% in male gerbils (60-85 g)[1].
References

[1]. Cheng FC, et al. Neuroprotective effects of sesamin and sesamolin on gerbil brain in cerebral ischemia. Int J Biomed Sci. 2006 Sep;2(3):284-8.

[2]. Shimizu S, et al. Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acidbiosynthesis. Lipids. 1991 Jul;26(7):512-6.

Density 1.4±0.1 g/cm3
Boiling Point 504.4±50.0 °C at 760 mmHg
Melting Point 122-124ºC
Molecular Formula C20H18O6
Molecular Weight 354.353
Flash Point 212.3±30.0 °C
Exact Mass 354.110352
PSA 55.38000
LogP 3.32
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.623
Storage condition −20°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2932999099
HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%