100307-95-7

100307-95-7 structure

Name: Abz-Ala-Gly-Leu-Ala-p-nitrobenzylamide
Chemical Name: 2-amino-N-[(2S)-1-[[2-[[(2S)-4-methyl-1-[[(2S)-2-[(4-nitrophenyl)methylamino]propanoyl]amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]benzamide
CAS Number: 100307-95-7
Molecular Formula: C₂₈H₃₇N₇O₇
Molecular Weight: 583.64
Catalog: Research Areas Others
Create Date: 2017-03-06 11:55:29
Modify Date: 2024-02-24 00:45:30
Abz-AGLA-Nba is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal[1].

Name	2-amino-N-[(2S)-1-[[2-[[(2S)-4-methyl-1-[[(2S)-2-[(4-nitrophenyl)methylamino]propanoyl]amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]benzamide
Synonyms	Aaglan Abz-ala-gly-leu-ala-nba 2-Aminobenzoylalanyl-glycyl-leucyl-alanyl-4-nitrobenzylamide 2-Aminobenzoyl-ala-gly-leu-ala-4-nitrobenzylamide L-Alaninamide,N-(2-aminobenzoyl)-L-alanylglycyl-L-leucyl-N-((4-nitrophenyl)methyl)-,(6aS-(6aalpha,7alpha,8beta,9aalpha))

Description	Abz-AGLA-Nba is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Everett MJ, et, al. Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models. ACS Infect Dis. 2023 Feb 10;9(2):270-282.