94361-06-5

94361-06-5 structure

Name: Cyproconazole
Chemical Name: cyproconazole
CAS Number: 94361-06-5
Molecular Formula: C₁₅H₁₈ClN₃O
Molecular Weight: 291.77600
Catalog: Chemical pesticide Fungicide Other fungicides
Create Date: 2018-08-08 18:13:57
Modify Date: 2024-01-02 17:20:16
Cyproconazole is a triazole fungicide that is used agriculturally for protection of crops against a wide variety of fungal pathogens.In vitro: Cyproconazole has been shown to cause a dose dependent inhibition of progesterone production in human placental cells in vitro. cyproconazole exhibited the lowest capacity to increase CYP1A1 and were not able to activate the AhR in the transactivation assay. [1]In vivo: Cyproconazole, a triazole fungicide, causes hepatocellular adenomas and carcinomas in CD-1 mice at dose levels of 100 and 200 ppm. In wild-type mice, 200 ppm cyproconazole caused liver hypertrophy, increased liver weight and cell proliferation, single-cell necrosis and fat vacuolation. [2]

Name	cyproconazole
Synonyms	1H-1,2,4-Triazole-1-ethanol,a-(4-chlorophenyl)-a-(1-cyclopropylethyl)- Cyproconazol 2RS,3SR)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol 2-(4-CHLOROPHENYL)-3-CYCLOPROPYL-1-(1,2,4-TRIAZOL-1-YL)BUTAN-2-OL 2-(4-Chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol rac-(2R,3RS)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol (2RS,3RS α-(4-chlorophenyl)-α-(1-cyclopropylethyl)-1H-1,2,4-triazole-1-ethanol MFCD01678672

Description	Cyproconazole is a triazole fungicide that is used agriculturally for protection of crops against a wide variety of fungal pathogens.In vitro: Cyproconazole has been shown to cause a dose dependent inhibition of progesterone production in human placental cells in vitro. cyproconazole exhibited the lowest capacity to increase CYP1A1 and were not able to activate the AhR in the transactivation assay. [1]In vivo: Cyproconazole, a triazole fungicide, causes hepatocellular adenomas and carcinomas in CD-1 mice at dose levels of 100 and 200 ppm. In wild-type mice, 200 ppm cyproconazole caused liver hypertrophy, increased liver weight and cell proliferation, single-cell necrosis and fat vacuolation. [2]
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Others
References	[1]. Rieke S et al. Combination effects of (tri)azole fungicides on hormone production and xenobiotic metabolism in a humanplacental cell line. Int J Environ Res Public Health. 2014 Sep 17;11(9):9660-79. [2]. Peffer RC et al. Mouse liver effects of cyproconazole, a triazole fungicide: role of the constitutive androstane receptor. Toxicol Sci. 2007 Sep;99(1):315-25.

Symbol	GHS07, GHS08, GHS09
Signal Word	Warning
Hazard Statements	H302-H361-H410
Precautionary Statements	P273-P281-P501
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	Xn
Risk Phrases	R22
Safety Phrases	S36/37-S60-S61
RIDADR	UN3077 9/PG 3
RTECS	XZ4803250
Hazard Class	9.0
HS Code	2933990015

HS Code	2933990015
Summary	2933990015 3-((1h-1,2,4-triazol-1-yl)methyl)-1-(4-chlorophenyl)-4,4-dimethylpentan-3-ol。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%