Name | fosinopril sodium |
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Synonyms |
Tensozide
Dynacil Fosinopril sodium (4S)-4-Cyclohexyl-1-{[(R)-[(1R)-2-methyl-1-(propionyloxy)propoxy](4-phenylbutyl)phosphoryl]acetyl}-L-proline Fosinorm Staril sodium,(2S,4S)-4-cyclohexyl-1-[2-[(2-methyl-1-propanoyloxypropoxy)-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylate (4S)-4-cyclohexyl-1-{[(R)-{[(1R)-2-methyl-1-(propanoyloxy)propyl]oxy}(4-phenylbutyl)phosphoryl]acetyl}-L-proline MFCD00897699 L-Proline, 4-cyclohexyl-1-[2-[(R)-[(1R)-2-methyl-1-(1-oxopropoxy)propoxy][(1R)-4-phenylbutyl]phosphinyl]acetyl]-, (4S)- Fositen L-proline, 4-cyclohexyl-1-[2-[(R)-[[(1R)-2-methyl-1-(1-oxopropoxy)propyl]oxy][(1R)-4-phenylbutyl]phosphinyl]acetyl]-, (4S)- Fozitec Elidur |
Description | Fosinopril Sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.Target: ACEFosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Fosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy [1-3]. |
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Related Catalog | |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 705.7±70.0 °C at 760 mmHg |
Melting Point | 196-198ºC |
Molecular Formula | C30H45NNaO7P |
Molecular Weight | 563.662 |
Flash Point | 380.6±35.7 °C |
Exact Mass | 563.301208 |
PSA | 122.85000 |
LogP | 6.09 |
Vapour Pressure | 0.0±2.4 mmHg at 25°C |
Index of Refraction | 1.532 |
Storage condition | -20°C Freezer |
RIDADR | NONH for all modes of transport |
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HS Code | 2933990090 |
HS Code | 2933990090 |
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Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |