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521-52-8

521-52-8 structure
521-52-8 structure
  • Name: Vulpic acid
  • Chemical Name: Vulpinic Acid
  • CAS Number: 521-52-8
  • Molecular Formula: C19H14O5
  • Molecular Weight: 322.31
  • Catalog: Biochemical Plant extracts
  • Create Date: 2018-06-08 20:24:53
  • Modify Date: 2024-01-13 21:33:41
  • Vulpinic acid, a lichen metabolite, decreases H2O2-induced ROS production, oxidative stress and oxidative stress-related damages in human umbilical vein endothelial cells (HUVEC). Vulpinic acid is active against staphylococci, enterococci, and anaerobic bacteria.Vulpinic acid has the potential for atherosclerosis research[1][2].

Name Vulpinic Acid
Synonyms vulpinic acid
Description Vulpinic acid, a lichen metabolite, decreases H2O2-induced ROS production, oxidative stress and oxidative stress-related damages in human umbilical vein endothelial cells (HUVEC). Vulpinic acid is active against staphylococci, enterococci, and anaerobic bacteria.Vulpinic acid has the potential for atherosclerosis research[1][2].
Related Catalog
References

[1]. E Sahin, et al. Vulpinic acid, a lichen metabolite, emerges as a potential drug candidate in the therapy of oxidative stress-related diseases, such as atherosclerosis. Hum Exp Toxicol. 2019 Jun;38(6):675-684.

[2]. M Lauterwein, et al. In vitro activities of the lichen secondary metabolites vulpinic acid, (+)-usnic acid, and (-)-usnic acid against aerobic and anaerobic microorganisms. Antimicrob Agents Chemother. 1995 Nov;39(11):2541-3.

Density 1.375g/cm3
Boiling Point 568.8ºC at 760mmHg
Melting Point 146-148ºC
Molecular Formula C19H14O5
Molecular Weight 322.31
Flash Point 210.2ºC
Exact Mass 322.08400
PSA 72.83000
LogP 3.09680
Index of Refraction 1.656
Storage condition -20°C Freezer

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HF3500000
CHEMICAL NAME :
Delta(sup 2(5H),alpha)-furanacetic acid, 3-hydroxy-5-oxo-alpha,4-diphenyl-, methyl ester
CAS REGISTRY NUMBER :
521-52-8
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C19-H14-O5
MOLECULAR WEIGHT :
322.33
WISWESSER LINE NOTATION :
T5VOYJ CUYR&VO1 DQ ER

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,30,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
75 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 2,109,1946
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02804
Risk Phrases 28
Safety Phrases 1-22-45
RIDADR UN 3172