4511-99-3

4511-99-3 structure
4511-99-3 structure
  • Name: 1,2,4-Triazin-3-amine,5,6-diphenyl-
  • Chemical Name: 5,6-diphenyl-1,2,4-triazin-3-amine
  • CAS Number: 4511-99-3
  • Molecular Formula: C15H12N4
  • Molecular Weight: 248.28300
  • Create Date: 2018-10-11 00:08:15
  • Modify Date: 2024-01-08 20:24:58

Name 5,6-diphenyl-1,2,4-triazin-3-amine
Synonyms 1,2,4-Triazin-3-amine,5,6-diphenyl
as-Triazine,3-amino-3,6-diphenyl
3-Amino-5,6-diphenyl-as-triazine
as-Triazine,3-amino-5,6-diphenyl
5,6-diphenyl-1,2,4-triazine-3-amine
3-Amino-5,6-diphenyl-1,2,4-triazine
Density 1.229g/cm3
Boiling Point 463.6ºC at 760mmHg
Melting Point 177ºC
Molecular Formula C15H12N4
Molecular Weight 248.28300
Flash Point 265.2ºC
Exact Mass 248.10600
PSA 64.69000
LogP 3.36900
Index of Refraction 1.653
Name: 5 6-Diphenyl-1 2 4-triazin-3-amine 97% Material Safety Data Sheet
Synonym:
CAS: 4511-99-3
Section 1 - Chemical Product MSDS Name:5 6-Diphenyl-1 2 4-triazin-3-amine 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
4511-99-3 5,6-Diphenyl-1,2,4-triazin-3-amine 97% unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 4511-99-3: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: cream
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 172 - 174 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C15H12N4
Molecular Weight: 248

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Acids, oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 4511-99-3: XY3177800 LD50/LC50:
Not available.
Carcinogenicity:
5,6-Diphenyl-1,2,4-triazin-3-amine - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 4511-99-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 4511-99-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 4511-99-3 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XY3177800
CHEMICAL NAME :
as-Triazine, 3-amino-3,6-diphenyl-
CAS REGISTRY NUMBER :
4511-99-3
BEILSTEIN REFERENCE NO. :
0207559
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C15-H12-N4
MOLECULAR WEIGHT :
248.31
WISWESSER LINE NOTATION :
T6NN DNJ CZ ER& FR&

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
145 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage)
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 95,123,1953
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 95,123,1953
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36/37/39
HS Code 2933699090

~41%

4511-99-3 structure

4511-99-3

Literature: Congreve, Miles; Andrews, Stephen P.; Dore, Andrew S.; Hollenstein, Kaspar; Hurrell, Edward; Langmead, Christopher J.; Mason, Jonathan S.; Ng, Irene W.; Tehan, Benjamin; Zhukov, Andrei; Weir, Malcolm; Marshall, Fiona H. Journal of Medicinal Chemistry, 2012 , vol. 55, # 5 p. 1898 - 1903

~72%

4511-99-3 structure

4511-99-3

Literature: El-Khoshnieh, Yehia O. Phosphorus, Sulfur and Silicon and Related Elements, 1998 , vol. 139, p. 163 - 172

~%

4511-99-3 structure

4511-99-3

Literature: Congreve, Miles; Andrews, Stephen P.; Dore, Andrew S.; Hollenstein, Kaspar; Hurrell, Edward; Langmead, Christopher J.; Mason, Jonathan S.; Ng, Irene W.; Tehan, Benjamin; Zhukov, Andrei; Weir, Malcolm; Marshall, Fiona H. Journal of Medicinal Chemistry, 2012 , vol. 55, # 5 p. 1898 - 1903

~88%

4511-99-3 structure

4511-99-3

Literature: El-Khoshnieh, Yehia O. Phosphorus, Sulfur and Silicon and Related Elements, 1998 , vol. 139, p. 163 - 172

~%

4511-99-3 structure

4511-99-3

Literature: HEPTARES THERAPEUTICS LIMITED; CONGREVE, Miles Stuart; ANDREWS, Stephen Philippe; MASON, Jonathan Stephen; RICHARDSON, Christine Mary; BROWN, Giles Albert Patent: WO2011/95625 A1, 2011 ; WO 2011/095625 A1

~%

4511-99-3 structure

4511-99-3

Literature: HEPTARES THERAPEUTICS LIMITED; CONGREVE, Miles Stuart; ANDREWS, Stephen Philippe; MASON, Jonathan Stephen; RICHARDSON, Christine Mary; BROWN, Giles Albert Patent: WO2011/95625 A1, 2011 ; WO 2011/095625 A1

~%

4511-99-3 structure

4511-99-3

Literature: El-Khoshnieh, Yehia O. Phosphorus, Sulfur and Silicon and Related Elements, 1998 , vol. 139, p. 163 - 172

~%

4511-99-3 structure

4511-99-3

Literature: Thiele; Bihan Justus Liebigs Annalen der Chemie, 1898 , vol. 302, p. 307
HS Code 2933699090
Summary 2933699090 other compounds containing an unfused triazine ring (whether or not hydrogenated) in the structure。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:20.0%