610300-00-0

610300-00-0 structure

Name: β-Amino Acid Imagabalin Hydrochloride
Chemical Name: (3S,5R)-3-amino-5-methyloctanoic acid,hydrochloride
CAS Number: 610300-00-0
Molecular Formula: C₉H₂₀ClNO₂
Molecular Weight: 209.71400
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2017-11-24 14:56:34
Modify Date: 2024-01-09 19:16:32
β-Amino Acid Imagabalin Hydrochloride (PD-0332334) is a ligand for the α2δ subunit of the voltage-dependent calcium channel.

Name	(3S,5R)-3-amino-5-methyloctanoic acid,hydrochloride
Synonyms	Imagabalin HCl UNII-MJ3F8ZA7Q1 β-Amino Acid Imagabalin Hydrochloride

Description	β-Amino Acid Imagabalin Hydrochloride (PD-0332334) is a ligand for the α2δ subunit of the voltage-dependent calcium channel.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Neurological Disease
Target	Calcium channel[1]
In Vivo	β-Amino Acid Imagabalin Hydrochloride had been in phase III clinical trials for the treatment of generalised anxiety disorders. However, this research has been discontinued[2]. β-Amino Acid Imagabalin Hydrochloride had been also in phase I clinical trials for the treatment of chronic kidney disease[3].
References	[1]. Birch M, et al. A Simplified Process for the Manufacture of Imagabalin Hydrochloride (PD-0332334), an α2δ-Ligand for the Treatment of Generalised Anxiety Disorder. Org. Process Res. Dev., 2011, 15 (6), pp 1358–1364