Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Oxametacin
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Huang

DC Chemicals Limited
China
Product Name: Oxametacin
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: oxametacin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

27035-30-9

27035-30-9 structure

27035-30-9 structure

Name: Oxametacin
Chemical Name: oxametacin
CAS Number: 27035-30-9
Molecular Formula: C₁₉H₁₇ClN₂O₄
Molecular Weight: 372.80200
Create Date: 2018-09-16 18:35:30
Modify Date: 2024-01-06 16:01:33
Oxametacin is a anti-inflammatory compound used with care in anticoagulated patients. It has analgesic, antipyretic and anti-inflammatory properties comparable to those of indomethacin.

Name	oxametacin
Synonyms	Oxametacinum [INN-Latin] Oxametacine [INN-French] Oxametacin 2-[1-(4-chloro-benzoyl)-5-methoxy-2-methyl-indol-3-yl]-N-hydroxy-acetamide Oxametacin [INN] Acido indoxamico [Italian] Indoxamic acid 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-hydroxyacetamide Oxametacine 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}ethanehydroxamic acid Oxametacina [INN-Spanish] 1-(4-chloro-benzoyl)-5-methoxy-2-methyl-3-indolyl-acetohydroxamic acid Oxamethacin 1-(p-chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetohydroxamic acid Flogar

Density	1.35g/cm3
Molecular Formula	C₁₉H₁₇ClN₂O₄
Molecular Weight	372.80200
Exact Mass	372.08800
PSA	80.56000
LogP	3.73900
Index of Refraction	1.63

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL3668500

CHEMICAL NAME :: Indole-3-acetohydroxamic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-

CAS REGISTRY NUMBER :: 27035-30-9

BEILSTEIN REFERENCE NO. :: 0497721

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H17-Cl-N2-O4

MOLECULAR WEIGHT :: 372.83

WISWESSER LINE NOTATION :: T56 BNJ BVR DG& C1 D1VMQ GO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 78 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 114,319,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 114,319,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 92 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 114,319,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 32 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 114,319,1975

HS Code	2933990090

20357-37-3 structure

20357-37-3

~%

27035-30-9 structure

27035-30-9

Literature: Wey, Shiow-Jyi; Augustyniak, Michael E.; Cochran, Edward D.; Ellis, James L.; Fang, Xinqin; Garvey, David S.; Janero, David R.; Letts, L. Gordon; Martino, Allison M.; Melim, Terry L.; Murty, Madhavi G.; Richardson, Steward K.; Schroeder, Joseph D.; Selig, William M.; Trocha, A. Mark; Wexler, Roseanne S.; Young, Delano V.; Zemtseva, Irina S.; Zifcak, Brian M. Journal of Medicinal Chemistry, 2007 , vol. 50, # 25 p. 6367 - 6382

53-86-1 structure

53-86-1

~%

27035-30-9 structure

27035-30-9

Literature: Flynn; Capiris; Cetenko; Connor; Dyer; Kostlan; Nies; Schrier; Sircar Journal of Medicinal Chemistry, 1990 , vol. 33, # 8 p. 2070 - 2072

Precursor 2
20357-37-3 53-86-1
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%