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83688-84-0

83688-84-0 structure
83688-84-0 structure
  • Name: Tertatolol
  • Chemical Name: 1-(3,4-Dihydro-2H-thiochromen-8-yloxy)-3-[(2-methyl-2-propanyl)am ino]-2-propanol
  • CAS Number: 83688-84-0
  • Molecular Formula: C16H25NO2S
  • Molecular Weight: 295.44000
  • Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
  • Create Date: 2016-03-17 02:14:09
  • Modify Date: 2024-01-18 07:20:02
  • Tertatolol is a potent antagonist of beta-adrenoceptor and 5-HT receptor, with unique renal vasodilatatory effects.

Name 1-(3,4-Dihydro-2H-thiochromen-8-yloxy)-3-[(2-methyl-2-propanyl)am ino]-2-propanol
Synonyms Tertatolol
Description Tertatolol is a potent antagonist of beta-adrenoceptor and 5-HT receptor, with unique renal vasodilatatory effects.
Related Catalog
In Vitro In serum-free media, tertatolol does not significantly alter the incorporation of 3H-thymidine after 28 h of incubation in human mesangial cell (HMC). In the presence of 1% serum, tertatolol significantly reduces 3H-thymidine incorporation. Tertatolol also inhibits 3H incorporation when PDGF and thrombin are used as the stimulus. Tertatolol inhibits the reduction in planar surface area of HMC induced by angiotensin II. The inhibitory effect of tertatolol on HMC proliferation is also potentiated by ritanserin and MDL 72222, 5HT2 and 5HT3 antagonists, respectively[1].
References

[1]. Shultz P, et al. Tertatolol: a beta-blocker with unique effects on human glomerular cell function. Cardiology. 1993;83 Suppl 1:51-6.

Molecular Formula C16H25NO2S
Molecular Weight 295.44000
Exact Mass 295.16100
PSA 66.79000
LogP 3.24360
Storage condition 2-8℃
HS Code 2932999099
HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%